Showing chemical card for 5-hydroxyindole acetate (CFc000337650)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:34 UTC
Chemfont ID
CFc000337650
Molecule Identification
Common Name
5-hydroxyindole acetate
Definition
5-hydroxyindoleacetic acid, also known as 5-hiaa or 5-hydroxy-1h-indole-3-acetate, belongs to indole-3-acetic acid derivatives class of compounds. Those are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. 5-hydroxyindoleacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 5-hydroxyindoleacetic acid can be found in a number of food items such as lemon thyme, green vegetables, alpine sweetvetch, and strawberry guava, which makes 5-hydroxyindoleacetic acid a potential biomarker for the consumption of these food products. 5-hydroxyindoleacetic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine, as well as throughout most human tissues. In humans, 5-hydroxyindoleacetic acid is involved in the tryptophan metabolism. Moreover, 5-hydroxyindoleacetic acid is found to be associated with sepiapterin reductase deficiency, schizophrenia, friedreich's ataxia, and olivopontocerebral atrophy. 5-Hydroxyindoleacetic acid (5-HIAA) is the main metabolite of serotonin. In chemical analysis of urine samples, 5-HIAA is used to determine serotonin levels in the body .
Belongs to the class of organic compounds known as indole-3-acetic acid derivatives. Indole-3-acetic acid derivatives are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole.
